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LIF Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05828G 100 μl / $495

LIF Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05828G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIF Antibody (Center).

Molecular Weight

22008 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

72-101 aa

Target

This LIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human LIF.

Isotype

Rabbit Ig

Symbol

HILDA

GeneID

UniProt ID

Function

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Summary

LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

Western blot analysis of lysates from rat PC-12 cell line, mouse spleen tissue lysate (from left to right), using LIF Antibody (Center)(APR05828G). APR05828G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Western blot analysis of LIF Antibody (Center) (Cat. APR05828G) in CEM cell line lysates (35ug/lane). LIF (arrow) was detected using the purified Pab.

Western blot analysis of LIF (arrow) using rabbit polyclonal LIF Antibody (Center) (Cat. APR05828G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LIF gene.

Specification

Quantity

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