> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HABP2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR05667G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HABP2 Antibody (C-term).
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Molecular Weight |
62672 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
378-408 aa
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Target |
This HABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-408 amino acids from the C-terminal region of human HABP2.
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Isotype |
Rabbit Ig
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Symbol |
HGFAL, PHBP
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GeneID |
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UniProt ID |
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Function |
Cleaves the alpha-chain at multiple sites and the beta- chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro- urokinase) to the active two chain form. Activates coagulation factor VII.
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Summary |
HABP2 is an extracellularserine protease that binds hyaluronic acid and is involved in celladhesion. The encoded protein is synthesized as a single chain, butthen undergoes an autoproteolytic event to form the functionalheterodimer. Further autoproteolysis leads to smaller, inactivepeptides. This protease is known to cleave urinary plasminogenactivator, coagulation factor VII, and the alpha and beta chains offibrinogen, but not prothrombin, plasminogen, or the gamma chain offibrinogen. Two transcript variants encoding different isoformshave been found for this gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:2000
IHC-P~~1:50~100
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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