> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TREM2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR05652G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TREM2 Antibody (N-term).
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Molecular Weight |
25447 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
22-50 aa
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Target |
This TREM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TREM2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
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Summary |
TREM2 is a membrane proteinthat forms a receptor signaling complex with TYROBP. The encodedprotein may be involved in chronic inflammation by triggering theproduction of constitutive inflammatory cytokines. Defects in thisgene are a cause of polycystic lipomembranous osteodysplasia withsclerosing leukoencephalopathy (PLOSL).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
TREM2 Antibody (N-term) (Cat.APR05652G) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TREM2 antibody detected the TREM2 protein (arrow). |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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