> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PTAFR Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR05645G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTAFR Antibody (C-term).
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Molecular Weight |
39203 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
286-312 aa
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Target |
This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.
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Isotype |
Rabbit Ig
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Symbol |
PAFR
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GeneID |
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UniProt ID |
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Function |
Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system.
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Summary |
PTAFR shows structural characteristics of the rhodopsin(MIM 180380) gene family and binds platelet-activating factor(PAF). PAF is a phospholipid(1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has beenimplicated as a mediator in diverse pathologic processes, such asallergy, asthma, septic shock, arterial thrombosis, andinflammatory processes.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
Anti-PTAFR Antibody (C-term) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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