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GMNN Antibody (Center Y111)

Catalog # Availability Size / Price Inquiry
APR05597G 100 μl / $495

GMNN Antibody (Center Y111)

Brand

Leading Biology

Catalog Number

APR05597G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GMNN Antibody (Center Y111).

Molecular Weight

23565 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus

Host

Rabbit

Species Reactivity

Human

Immunogen

96-123 aa

Target

This GMNN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human GMNN.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Summary

GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

Western blot analysis of GMNN Antibody (Center Y111) (Cat. APR05597G) in HepG2 cell line lysates (35ug/lane).GMNN (arrow) was detected using the purified Pab.

GMNN Antibody (Center Y111) (Cat. APR05597G) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMNN Antibody (Center Y111) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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