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KLHL9 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05580G 100 μl / $495

KLHL9 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05580G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLHL9 Antibody (Center).

Molecular Weight

69429 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

299-326 aa

Target

This KLHL9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-326 amino acids from the Central region of human KLHL9.

Isotype

Rabbit Ig

Symbol

KIAA1354

GeneID

UniProt ID

Function

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.

Summary

KLHL9 is substrate-specific adapter for a CUL3-based E3 ubiquitin-protein ligase complex. Within this complex, it controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

Western blot analysis of KLHL9 Antibody (Center) (Cat. APR05580G) in mouse testis tissue lysates (35ug/lane).KLHL9 (arrow) was detected using the purified Pab.

KLHL9 Antibody (Center) (Cat. APR05580G) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KLHL9 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

KLHL9 Antibody (Center) (Cat. APR05580G) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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