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Polyclonal Antibodies >
KLHL9 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR05580G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLHL9 Antibody (Center).
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Molecular Weight |
69429 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
299-326 aa
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Target |
This KLHL9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-326 amino acids from the Central region of human KLHL9.
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Isotype |
Rabbit Ig
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Symbol |
KIAA1354
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GeneID |
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UniProt ID |
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Function |
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
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Summary |
KLHL9 is substrate-specific adapter for a CUL3-based E3 ubiquitin-protein ligase complex. Within this complex, it controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Images |
Western blot analysis of KLHL9 Antibody (Center) (Cat. APR05580G) in mouse testis tissue lysates (35ug/lane).KLHL9 (arrow) was detected using the purified Pab. KLHL9 Antibody (Center) (Cat. APR05580G) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KLHL9 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. KLHL9 Antibody (Center) (Cat. APR05580G) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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