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HSD17B2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05529G 100 μl / $495

HSD17B2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05529G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSD17B2 Antibody (Center).

Molecular Weight

42785 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

265-294 aa

Target

This HSD17B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human HSD17B2.

Isotype

Rabbit Ig

Symbol

EDH17B2

GeneID

UniProt ID

Function

Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.

Summary

HSD17B2 is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone.HSD17B2 also has 20-alpha-HSD activity. HSD17B2 uses NADH while EDH17B3 uses NADPH.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

Anti-HSD17B2 Antibody (Center) at 1:1000 dilution + MDA-MB-453 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

HSD17B2 Antibody (Center) (Cat. APR05529G) IHC analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HSD17B2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

HSD17B2 Antibody (Center) (Cat. APR05529G) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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