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TNF12 Antibody

Catalog # Availability Size / Price Inquiry
APR05411G 100 μl / $495

TNF12 Antibody

Brand

Leading Biology

Catalog Number

APR05411G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNF12 Antibody.

Molecular Weight

27, 37 KDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type II membrane protein Isoform TWE-PRIL: Cell membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

62-90 aa

Symbol

APO3L, DR3LG

GeneID

UniProt ID

Function

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Summary

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, IHC

Dilution

WB~~ 1:1000 IF~~1:100 IHC~~1:50-1:100

Images

Western blot analysis of lysates from 293,HUVEC cell line (from left to right),using TNF12 Antibody(APR05411G). APR05411G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

Immunofluorescence analysis of HeLa cells, using TNF12 antibody.

Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.

Specification

Quantity

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