> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Phospho-CCNB3(T280) AntibodyBrand |
Leading Biology | Catalog Number |
APR05321G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-CCNB3(T280) Antibody.
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Molecular Weight |
157916 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.
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Isotype |
Rabbit Ig
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Symbol |
CYCB3
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GeneID |
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UniProt ID |
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Function |
Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I.
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Summary |
The protein encoded by this gene belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event.Studies of similar genes in chick and Drosophila suggest that thiscyclin may associate with CDC2 and CDK2 kinases, and be requiredfor proper spindle reorganization and restoration of the interphasenucleus. Two transcript variants encoding different isoforms havebeen found for this gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
DB, E
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Dilution |
DB~~1:500
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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