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GDF1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04640G 100 μl / $495

GDF1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04640G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GDF1 Antibody (N-term).

Molecular Weight

39475 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

30-59 aa

Target

This GDF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human GDF1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May mediate cell differentiation events during embryonic development.

Summary

GDF1 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right assymetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA which also encodes the longevity assurance gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

Western blot analysis of GDF1 Antibody (N-term) (Cat. APR04640G) in HepG2 cell line lysates (35ug/lane). GDF1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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