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CCL17 Antibody(C-term)

Catalog # Availability Size / Price Inquiry
APR04452G 100 μl / $495

CCL17 Antibody(C-term)

Brand

Leading Biology

Catalog Number

APR04452G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCL17 Antibody(C-term).

Molecular Weight

10507 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

65-94 aa

Target

This CCL17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the C-terminal region of human CCL17.

Isotype

Rabbit Ig

Symbol

SCYA17, TARC

GeneID

UniProt ID

Function

Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

Summary

This gene is one of several Cys-Cys (CC) cytokine genesclustered on the q arm of chromosome 16. Cytokines are a family ofsecreted proteins involved in immunoregulatory and inflammatoryprocesses. The CC cytokines are proteins characterized by twoadjacent cysteines. The cytokine encoded by this gene displayschemotactic activity for T lymphocytes, but not monocytes orgranulocytes. The product of this gene binds to chemokine receptorsCCR4 and CCR8. This chemokine plays important roles in T celldevelopment in thymus as well as in trafficking and activation ofmature T cells.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-CCL17 Antibody (C-term) at 1:1000 dilution + NCI-H460 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 11 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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