> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SEPT12 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04417G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPT12 Antibody (Center).
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Molecular Weight |
40748 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell projection, cilium, flagellum. Note=At interphase, forms a filamentous structure in the cytoplasm. During anaphase, translocates to the central spindle region and to the midbody during cytokinesis. Found in the sperm annulus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
218-244 aa
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Target |
This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
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Summary |
Septins, such as SEPT12, are conserved GTP-bindingproteins that function as dynamic, regulatable scaffolds for therecruitment of other proteins. They are involved in membranedynamics, vesicle trafficking, apoptosis, and cytoskeletonremodeling, as well as infection, neurodegeneration, and neoplasia(Hall et al., 2005 [PubMed 15915442]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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