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OSTM1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04305G 100 μl / $495

OSTM1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04305G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OSTM1 Antibody (C-term).

Molecular Weight

37257 Da

Cellular Localization

Antigen Cellular Localization: Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel to lysosomes

Host

Rabbit

Species Reactivity

Human

Immunogen

292-321 aa

Target

This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.

Isotype

Rabbit Ig

Symbol

GL

GeneID

UniProt ID

Function

Required for osteoclast and melanocyte maturation and function.

Summary

This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

OSTM1 Antibody (C-term) (Cat. APR04305G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OSTM1 Antibody detected the OSTM1 protein (arrow).

Specification

Quantity

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