> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HAUS8 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR04297G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HAUS8 Antibody (N-term).
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Molecular Weight |
44857 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
28-54 aa
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Target |
This HAUS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of human HAUS8.
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Isotype |
Rabbit Ig
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Symbol |
HICE1
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GeneID |
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UniProt ID |
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Function |
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
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Summary |
HAUS8 is 1 of 8 subunits of the 390-kD human augmincomplex, or HAUS complex. The augmin complex was first identifiedin Drosophila, and its name comes from the Latin verb 'augmentare,'meaning 'to increase.' The augmin complex is a microtubule-bindingcomplex involved in microtubule generation within the mitoticspindle and is vital to mitotic spindle assembly (Goshima et al.,2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed19369198]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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