> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MND1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04282G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MND1 Antibody (C-term).
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Molecular Weight |
23753 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
174-200 aa
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Target |
This MND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the C-terminal region of human MND1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
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Summary |
The product of the MND1 gene associates with HOP2 (MIM608665) to form a stable heterodimeric complex that binds DNA andstimulates the recombinase activity of RAD51 (MIM 179617) and DMC1(MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1and HOP2 genes are indispensable for meioticrecombination.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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