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COL8A1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04198G 100 μl / $495

COL8A1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04198G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COL8A1 Antibody (N-term).

Molecular Weight

73364 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

62-89 aa

Target

This COL8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the N-terminal region of human COL8A1.

Isotype

Rabbit Ig

Symbol

C3orf7

GeneID

UniProt ID

Function

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

Summary

This gene encodes one of the two alpha chains of type VIIIcollagen. The gene product is a short chain collagen and a majorcomponent of the basement membrane of the corneal endothelium. Thetype VIII collagen fibril can be either a homo- or a heterotrimer.Alternatively spliced transcript variants encoding the same isoformhave been observed.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

All lanes : Anti-COL8A1 Antibody (N-term) at 1:1000 dilution Lane 1: human heart lysate Lane 2: human liver lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 73 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

COL8A1 Antibody (N-term) (Cat. APR04198G) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the COL8A1 antibody detected the COL8A1 protein (arrow).

Specification

Quantity

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