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MMRN1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04173G 100 μl / $495

MMRN1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04173G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MMRN1 Antibody (N-term).

Molecular Weight

138110 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

179-207 aa

Target

This MMRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human MMRN1.

Isotype

Rabbit Ig

Symbol

ECM, EMILIN4, GPIA*, MMRN

GeneID

UniProt ID

Function

Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.

Summary

Multimerin is a massive, soluble protein found inplatelets and in the endothelium of blood vessels. It is comprisedof subunits linked by interchain disulfide bonds to form large,variably sized homomultimers. Multimerin is a factor V/Va-bindingprotein and may function as a carrier protein for platelet factorV. It may also have functions as an extracellular matrix oradhesive protein. Recently, patients with an unusualautosomal-dominant bleeding disorder (factor V Quebec) were foundto have a deficiency of platelet multimerin.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody (N-term)(APR04173G). APR04173G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Specification

Quantity

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