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TRPC1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04147G 100 μl / $495

TRPC1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04147G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRPC1 Antibody (C-term).

Molecular Weight

91212 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

765-793 aa

Target

This TRPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 765-793 amino acids from the C-terminal region of human TRPC1.

Isotype

Rabbit Ig

Symbol

TRP1

GeneID

UniProt ID

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Summary

TRPC1 belongs to the transient receptor potential (TRP)superfamily of cation channels. TRP cation channels are involved indiverse physiologic processes, including receptor- andstore-operated Ca(2+) entry, mineral absorption, and cell death.They also function as sensors for pain, heat, cold, sound, stretch,and osmotic changes (Zhang et al., 2009 [PubMed19193631]).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-TRPC1 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 91 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

TRPC1 Antibody (C-term) (Cat. APR04147G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TRPC1 antibody detected the TRPC1 protein (arrow).

Specification

Quantity

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