> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ISG20 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04121G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ISG20 Antibody (Center).
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Molecular Weight |
20363 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
29-58 aa
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Target |
This ISG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the Central region of human ISG20.
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Isotype |
Rabbit Ig
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Symbol |
HEM45
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GeneID |
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UniProt ID |
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Function |
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
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Summary |
Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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