> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KRAS Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04099G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KRAS Antibody (C-term).
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Molecular Weight |
21656 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Immunogen |
146-174 aa
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Target |
This KRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the C-terminal region of human KRAS.
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Isotype |
Rabbit Ig
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Symbol |
KRAS2, RASK2
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GeneID |
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UniProt ID |
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Function |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838).
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Summary |
This gene, a Kirsten ras oncogene homolog from themammalian ras gene family, encodes a protein that is a member ofthe small GTPase superfamily. A single amino acid substitution isresponsible for an activating mutation. The transforming proteinthat results is implicated in various malignancies, including lungadenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreasand colorectal carcinoma. Alternative splicing leads to variantsencoding two isoforms that differ in the C-terminal region.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, FC, E
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Dilution |
WB~~1:2000
IF~~1:10~50
FC~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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