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Polyclonal Antibodies >
MAS1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR03929G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAS1 Antibody (C-term).
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Molecular Weight |
37465 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
285-314 aa
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Target |
This MAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human MAS1.
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Isotype |
Rabbit Ig
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Symbol |
MAS
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GeneID |
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UniProt ID |
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Function |
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
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Summary |
The structure of the MAS1 product indicates that itbelongs to the class of receptors that are coupled to GTP-bindingproteins and share a conserved structural motif, which is describedas a '7-transmembrane segment' following the prediction that thesehydrophobic segments form membrane-spanning alpha-helices. The MAS1protein may be a receptor that, when activated, modulates acritical component in a growth-regulating pathway to bring aboutoncogenic effects.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
MAS1 Antibody (C-term) (Cat. APR03929G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAS1 antibody detected the MAS1 protein (arrow). |
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Specification |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask | ||
2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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3 | Leading Biology | APR13816G | TRPM5 Antibody | 50 μl | Polyclonal Antibodies |
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$695.00 | Add Ask | ||
4 | Leading Biology | APR04506G | PCOLCE2 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask | ||
5 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
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$495.00 | Add Ask | |
6 | Leading Biology | APR05221G | Phospho-SMAD2(S118) Antibody | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
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