> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > WNT8B Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR03890G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality WNT8B Antibody (C-term).
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Molecular Weight |
38721 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
323-351 aa
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Target |
This WNT8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human WNT8B.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.
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Summary |
The WNT gene family consists of structurally related geneswhich encode secreted signaling proteins. These proteins have beenimplicated in oncogenesis and in several developmental processes,including regulation of cell fate and patterning duringembryogenesis. This gene is a member of the WNT gene family. Itencodes a protein which shows 95%, 86% and 71% amino acid identityto the mouse, zebrafish and Xenopus Wnt8B proteins, respectively.The expression patterns of the human and mouse genes appearidentical and are restricted to the developing brain. Thechromosomal location of this gene to 10q24 suggests it as acandidate gene for partial epilepsy.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
Anti-WNT8B Antibody (C-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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