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WNT8B Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03890G 100 μl / $495

WNT8B Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03890G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WNT8B Antibody (C-term).

Molecular Weight

38721 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human

Immunogen

323-351 aa

Target

This WNT8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human WNT8B.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.

Summary

The WNT gene family consists of structurally related geneswhich encode secreted signaling proteins. These proteins have beenimplicated in oncogenesis and in several developmental processes,including regulation of cell fate and patterning duringembryogenesis. This gene is a member of the WNT gene family. Itencodes a protein which shows 95%, 86% and 71% amino acid identityto the mouse, zebrafish and Xenopus Wnt8B proteins, respectively.The expression patterns of the human and mouse genes appearidentical and are restricted to the developing brain. Thechromosomal location of this gene to 10q24 suggests it as acandidate gene for partial epilepsy.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-WNT8B Antibody (C-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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