> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MMP8 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03853G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP8 Antibody (N-term).
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Molecular Weight |
53412 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granules
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
56-84 aa
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Target |
This MMP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human MMP8.
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Isotype |
Rabbit Ig
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Symbol |
CLG1
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GeneID |
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UniProt ID |
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Function |
Can degrade fibrillar type I, II, and III collagens.
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Summary |
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. However, the enzyme encoded by thisgene is stored in secondary granules within neutrophils and isactivated by autolytic cleavage. Its function is degradation oftype I, II and III collagens. The gene is part of a cluster of MMPgenes which localize to chromosome 11q22.3.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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