> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TNFRSF10A Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR03849G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TNFRSF10A Antibody (C-term).
|
||
Molecular Weight |
50089 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human
|
||
Immunogen |
418-446 aa
|
||
Target |
This TNFRSF10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the C-terminal region of human TNFRSF10A.
|
||
Isotype |
Rabbit Ig
|
||
Symbol |
APO2, DR4, TRAILR1
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B.
|
||
Summary |
The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is activated by tumornecrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL),and thus transduces cell death signal and induces cell apoptosis.Studies with FADD-deficient mice suggested that FADD, a deathdomain containing adaptor protein, is required for the apoptosismediated by this protein.
|
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, E
|
||
Dilution |
WB~~1:1000
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
