> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HBG1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR03847G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HBG1 Antibody (Center).
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Molecular Weight |
16140 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
56-85 aa
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Target |
This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
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Summary |
The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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