> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KLRC1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03712G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLRC1 Antibody (N-term).
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Molecular Weight |
26314 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1.
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Isotype |
Rabbit Ig
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Symbol |
NKG2A
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GeneID |
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UniProt ID |
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Function |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
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Summary |
Natural killer (NK) cells are lymphocytes that can mediatelysis of certain tumor cells and virus-infected cells withoutprevious activation. They can also regulate specific humoral andcell-mediated immunity. The protein encoded by this gene belongs tothe killer cell lectin-like receptor family, also called NKG2family, which is a group of transmembrane proteins preferentiallyexpressed in NK cells. This family of proteins is characterized bythe type II membrane orientation and the presence of a C-typelectin domain. This protein forms a complex with another familymember, KLRD1/CD94, and has been implicated in the recognition ofthe MHC class I HLA-E molecules in NK cells. The genes of NKG2family members form a killer cell lectin-like receptor gene clusteron chromosome 12. Four alternatively spliced transcript variantsencoding two distinct isoforms have been observed. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, E
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Dilution |
WB~~1:1000
IF~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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