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PITRM1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03686G 100 μl / $495

PITRM1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03686G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PITRM1 Antibody (Center).

Molecular Weight

117413 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion matrix

Host

Rabbit

Species Reactivity

Human

Immunogen

490-518 aa

Target

This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

Isotype

Rabbit Ig

Symbol

KIAA1104, MP1

GeneID

UniProt ID

Function

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Summary

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

PITRM1 Antibody (Center) (Cat. APR03686G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PITRM1 antibody detected the PITRM1 protein (arrow).

Specification

Quantity

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