> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PDCD1LG2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03672G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDCD1LG2 Antibody (N-term).
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Molecular Weight |
30957 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 3: Secreted. Isoform 1: Cell membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
46-75 aa
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Target |
This PDCD1LG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human PDCD1LG2.
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Isotype |
Rabbit Ig
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Symbol |
B7DC, CD273, PDCD1L2, PDL2
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GeneID |
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UniProt ID |
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Function |
Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
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Summary |
PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
All lanes : Anti-PDCD1LG2 Antibody (N-term) at 1:1000-1:2000 dilution Lane 1: A549 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Raji whole cell lysate Lane 4: ZR-75-1 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
PDCD1LG2 Antibody (N-term) (Cat. APR03672G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDCD1LG2 antibody detected the PDCD1LG2 protein (arrow).
PDCD1LG2 Antibody (N-term) (Cat. APR03672G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDCD1LG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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