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HAUS3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03551G 100 μl / $495

HAUS3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03551G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HAUS3 Antibody (Center).

Molecular Weight

69650 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle Note=Localizes to interphase centrosomes and to mitotic spindle microtubules

Host

Rabbit

Species Reactivity

Human

Immunogen

372-400 aa

Target

This HAUS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-400 amino acids from the Central region of human HAUS3.

Isotype

Rabbit Ig

Symbol

C4orf15

GeneID

UniProt ID

Function

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Summary

HAUS3 is 1 of 8 subunits of the 390-kD human augmincomplex, or HAUS complex. The augmin complex was first identifiedin Drosophila, and its name comes from the Latin verb 'augmentare,'meaning 'to increase.' The augmin complex is a microtubule-bindingcomplex involved in microtubule generation within the mitoticspindle and is vital to mitotic spindle assembly (Goshima et al.,2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed19369198]).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

HAUS3 Antibody (Center) (Cat. APR03551G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the HAUS3 antibody detected the HAUS3 protein (arrow).

HAUS3 Antibody (Center) (Cat. APR03551G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HAUS3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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