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FBXO18 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03539G 100 μl / $495

FBXO18 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03539G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXO18 Antibody (C-term).

Molecular Weight

117686 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Mouse

Immunogen

741-769 aa

Target

This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 amino acids from the C-terminal region of human FBXO18.

Isotype

Rabbit Ig

Symbol

FBH1, FBX18

GeneID

UniProt ID

Function

DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction.

Summary

This gene encodes a member of the F-box protein family,members of which are characterized by an approximately 40 aminoacid motif, the F-box. The F-box proteins constitute one of thefour subunits of ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into three classes:Fbws containing WD-40 domains, Fbls containing leucine-richrepeats, and Fbxs containing either different protein-proteininteraction modules or no recognizable motifs. The protein encodedby this gene belongs to the Fbx class. It contains an F-box motifand seven conserved helicase motifs, and has both DNA-dependentATPase and DNA unwinding activities. Alternatively splicedtranscript variants encoding distinct isoforms have been identifiedfor this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

FBXO18 Antibody (C-term) (Cat. APR03539G) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FBXO18 antibody detected the FBXO18 protein (arrow).

Specification

Quantity

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