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WIPF2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03507G 100 μl / $495

WIPF2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03507G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WIPF2 Antibody (C-term).

Molecular Weight

46289 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton Note=Localized to stress fibers and bundles of actin filaments

Host

Rabbit

Species Reactivity

Human

Immunogen

392-419 aa

Target

This WIPF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-419 amino acids from the C-terminal region of human WIPF2.

Isotype

Rabbit Ig

Symbol

WICH, WIRE

GeneID

UniProt ID

Function

Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.

Summary

This gene encodes a WASP interacting protein (WIP)-relatedprotein. It has been shown that this protein has a role in theWASP-mediated organization of the actin cytoskeleton and that thisprotein is a potential link between the activated platelet-derivedgrowth factor receptor and the actin polymerization machinery.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

WIPF2 Antibody (C-term) (Cat. APR03507G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WIPF2 antibody detected the WIPF2 protein (arrow).

WIPF2 antibody (C-term) (Cat. APR03507G) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WIPF2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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