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BCL11B Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03503G 100 μl / $495

BCL11B Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03503G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BCL11B Antibody (Center).

Molecular Weight

95519 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human

Immunogen

307-334 aa

Target

This BCL11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-334 amino acids from the Central region of human BCL11B.

Isotype

Rabbit Ig

Symbol

CTIP2, RIT1

GeneID

UniProt ID

Function

Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity).

Summary

This gene encodes a C2H2-type zinc finger protein and isclosely related to BCL11A, a gene whose translocation may beassociated with B-cell malignancies. The specific function of thisgene has not yet been determined. Two alternatively splicedtranscript variants, which encode distinct isoforms, have beenreported.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:16000

Images

All lanes : Anti-BCL11B Antibody (Center) at 1:16000 dilution Lane 1: Jurkat whole cell lysate Lane 2: MOLT-4 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 96 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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