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CASC4 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03445G 100 μl / $495

CASC4 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03445G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASC4 Antibody (C-term).

Molecular Weight

48864 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

336-365 aa

Target

This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Summary

The increased expression level of this gene is associatedwith HER-2/neu proto-oncogene overexpression. Amplification andresulting overexpression of this proto-oncogene are found inapproximately 30% of human breast and 20% of human ovarian cancers.Further characterization of the product of this gene may yieldinsight into the fundamental biology and pathogenetic effects ofHER-2/neu overexpression in human breast and ovarian cancer cells.Alternatively spliced variants encoding different isoforms havebeen identified for this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

CASC4 Antibody (C-term) (Cat. APR03445G) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).

CASC4 Antibody (C-term) (Cat. APR03445G) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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