> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > BRD2 polyclonal antibodyBrand |
Leading Biology | Catalog Number |
APR00374G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BRD2 polyclonal antibody.
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Molecular Weight |
88061 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Note=Detected on chromatin and nucleosomes
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Host |
Rabbit
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Target |
BRD2
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Isotype |
Rabbit IgG
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Symbol |
KIAA9001, RING3
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GeneID |
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UniProt ID |
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Function |
May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.
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Summary |
Brd2, a mitogen-activated kinase localized to the nucleus, is a putative transcriptional regulator which interacts with E2F1 and with histone H4 acetylated at ‘Lys-13’. It is expressed during development and may be involved in growth control. Brd2 also may play a role in spermatogenesis or folliculogenesis and may be involved in some types of leukemia and in juvenile myoclonic epilepsy.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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