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GZMA Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APG00588G 0.1mg / $495

GZMA Antibody (internal region)

Brand

Leading Biology

Catalog Number

APG00588G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GZMA Antibody (internal region).

Molecular Weight

28999 Da

Cellular Localization

Antigen Cellular Localization: Isoform alpha: Secreted. Cytoplasmic granule

Host

Goat

Isotype

IgG

Symbol

CTLA3, HFSP

GeneID

UniProt ID

Function

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Images

Specification

Quantity

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