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Human IL1R1/Interleukin-1 receptor type 1 ELISA KitBrand |
Leading Biology | Catalog Number |
EK00131E |
Product Type |
ELISA Kit | Field of Research |
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Product Overview |
EK00131E is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Interleukin-1 receptor type 1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Interleukin-1 receptor type 1 The ELISA analytical biochemical technique of the EK00131E kit is based on Interleukin-1 receptor type 1 antibody-Interleukin-1 receptor type 1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Interleukin-1 receptor type 1 antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Interleukin-1 receptor type 1. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV (%).
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Cellular Localization |
Membrane Single-pass type I membrane protein Cell membrane Secreted
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Assay Type |
Sandwich
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Detection Method |
Spectrophotometrical
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Reactivity |
Human
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Sample Type |
This immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.
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Sensitivity |
0.056 ng/mL
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Assay Range |
0.156-10 ng/mL
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Kit Components |
Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.
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Other Reagents Required |
Deionized or distilled water
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Gene Name |
IL1R1
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MIM |
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UniProt ID |
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Function |
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
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Form |
ELISA Kits |
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Storage & Stability |
Store at +4°C. Please refer to protocols.
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Applications |
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
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Synonyms |
IL-1R-1,CD121 antigen-like family member A,Interleukin-1 receptor alpha,IL-1R-alpha,Interleukin-1 receptor type I,p80,CD121a,IL1R,IL1RA,IL1RT1
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Images |
Standard curve of the product EK00131E. |
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Specification |
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Quantity |
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