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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Immunoassay Kits > ELISA Kit > Human IL1R1/Interleukin-1 receptor type 1 ELISA Kit

Human IL1R1/Interleukin-1 receptor type 1 ELISA Kit

Catalog # Availability Size / Price Inquiry
EK00131E 96T / $545

Human IL1R1/Interleukin-1 receptor type 1 ELISA Kit

Brand

Leading Biology

Catalog Number

EK00131E

Product Type

ELISA Kit

Field of Research

Product Overview

EK00131E is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin and Metalloprotease 30 (Interleukin-1 receptor type 1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Interleukin-1 receptor type 1 The ELISA analytical biochemical technique of the EK00131E kit is based on Interleukin-1 receptor type 1 antibody-Interleukin-1 receptor type 1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Interleukin-1 receptor type 1 antigen targets in samples. The ELISA Kit is designed to detect native, recombinant, Interleukin-1 receptor type 1. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV (%).

Cellular Localization

Membrane Single-pass type I membrane protein Cell membrane Secreted

Assay Type

Sandwich

Detection Method

Spectrophotometrical

Reactivity

Human

Sample Type

This immunoassay kit allows for the in vitro quantitative determination in Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

Sensitivity

0.056 ng/mL

Assay Range

0.156-10 ng/mL

Kit Components

Assay Plate, Standard, Sample Diluent, Assay Diluent A&B, Detection Reagent A&B, Wash Buffer, Substrate, Stop Solution.

Other Reagents Required

Deionized or distilled water

Gene Name

IL1R1

MIM

UniProt ID

Function

Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Form

ELISA Kits

Storage & Stability

Store at +4°C. Please refer to protocols.

Applications

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

Synonyms

IL-1R-1,CD121 antigen-like family member A,Interleukin-1 receptor alpha,IL-1R-alpha,Interleukin-1 receptor type I,p80,CD121a,IL1R,IL1RA,IL1RT1

Images

Standard curve of the product EK00131E.

Specification

Quantity

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