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PSPC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28537N-1 50ul / $395
APR28537N-2 100ul / $495
APR28537N-3 200ul / $595

PSPC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28537N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSPC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 45kDa/58kDa Observed MW: 65kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PSPC1 (NP_001035879.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IP

Dilution

WB 1:500 - 1:2000 IP 1:50 - 1:200

Product Description

This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

Synonyms

PSPC1; PSP1; paraspeckle component 1

Images

Western blot analysis of extracts of various cell lines, using PSPC1 antibody.

Specification

Quantity

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