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IYD Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28536N-1 50ul / $395
APR28536N-2 100ul / $495
APR28536N-3 200ul / $595

IYD Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28536N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IYD Polyclonal Antibody.

Molecular Weight

Calculated MW: 22kDa/28kDa/31kDa/32kDa/33kDa Observed MW: 25kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IYD (NP_981932.1).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:200 - 1:2000

Product Description

This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.

Synonyms

IYD; C6orf71; DEHAL1; IYD-1; TDH4; iodotyrosine deiodinase

Images

Western blot analysis of extracts of various cell lines, using IYD antibody.

Specification

Quantity

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