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INHBB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28333N-1 50ul / $395
APR28333N-2 100ul / $495
APR28333N-3 200ul / $595

INHBB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28333N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cytokines

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality INHBB Polyclonal Antibody.

Molecular Weight

Calculated MW: 45kDa Observed MW: 45kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human INHBB (NP_002184.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Synonyms

INHBB; inhibin beta B chain

Images

Western blot analysis of extracts of various cell lines, using INHBB antibody.

Immunohistochemistry of paraffin-embedded mouse lung using INHBB antibody.

Specification

Quantity

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