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IL5RA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28332N-1 50ul / $395
APR28332N-2 100ul / $495
APR28332N-3 200ul / $595

IL5RA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28332N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL5RA Polyclonal Antibody.

Molecular Weight

Calculated MW: 23kDa/37kDa/42kDa/47kDa Observed MW: 76kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IL5RA (NP_783855.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Synonyms

IL5RA; CD125; CDw125; HSIL5R3; IL5R; interleukin-5 receptor subunit alpha

Images

Western blot analysis of extracts of various cell lines, using IL5RA antibody.

Specification

Quantity

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