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HRG Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28218N-1 50ul / $395
APR28218N-2 100ul / $495
APR28218N-3 200ul / $595

HRG Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28218N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HRG Polyclonal Antibody.

Molecular Weight

Calculated MW: 59kDa Observed MW: 80kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HRG (NP_000403.1).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Synonyms

HRG; HPRG; HRGP; THPH11; histidine-rich glycoprotein

Images

Western blot analysis of extracts of mouse pancreas, using HRG antibody.

Immunohistochemistry of paraffin-embedded rat lung using HRG antibody.

Immunohistochemistry of paraffin-embedded mouse lung using HRG antibody.

Specification

Quantity

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