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HNRNPL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR28217N-1 50ul / $395
APR28217N-2 100ul / $495
APR28217N-3 200ul / $595

HNRNPL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR28217N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRNPL Polyclonal Antibody.

Molecular Weight

Calculated MW: 50kDa/64kDa Observed MW: 64kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HNRNPL (NP_001524.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

HNRNPL; HNRPL; P/OKcl.14; hnRNP-L; heterogeneous nuclear ribonucleoprotein L

Images

Western blot analysis of extracts of various cell lines, using HNRNPL antibody.

Immunohistochemistry of paraffin-embedded human stomach using HNRNPL antibody.

Immunohistochemistry of paraffin-embedded rat kidney using HNRNPL antibody.

Specification

Quantity

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