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CLK2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27784N-1 50ul / $395
APR27784N-2 100ul / $495
APR27784N-3 200ul / $595

CLK2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27784N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLK2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/59kDa/60kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CLK2 (NP_003984.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

Synonyms

CLK2; CDC like kinase 2

Images

Western blot analysis of extracts of various cell lines, using CLK2 antibody.

Specification

Quantity

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