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CHRNG Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27783N-1 50ul / $395
APR27783N-2 100ul / $495
APR27783N-3 200ul / $595

CHRNG Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27783N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHRNG Polyclonal Antibody.

Molecular Weight

Calculated MW: 52kDa/57kDa Observed MW: 60KDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CHRNG (NP_005190.4).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

Synonyms

CHRNG; ACHRG; acetylcholine receptor subunit gamma

Images

Western blot analysis of extracts of various cell lines, using CHRNG antibody.

Specification

Quantity

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