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NCOR1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27055N-1 50ul / $395
APR27055N-2 100ul / $495
APR27055N-3 200ul / $595

NCOR1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27055N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>ErbB-HER Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NCOR1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 103kDa/258kDa/270kDa Observed MW: 320kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NCOR1 (NP_006302.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Synonyms

NCOR1; N-CoR; N-CoR1; PPP1R109; TRAC1; hN-CoR; nuclear receptor corepressor 1

Images

Western blot analysis of extracts of various cell lines, using NCOR1 antibody.

Immunofluorescence analysis of U2OS cells using NCOR1 antibody.

Specification

Quantity

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