> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > mH2A1 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR27054N |
Product Type |
Polyclonal Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>Histones |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality mH2A1 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
39kDa
Observed MW:
40kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human H2AFY (NP_613258.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
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Product Description |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Synonyms |
H2AFY; H2A.y; H2A/y; H2AF12M; MACROH2A1.1; mH2A1; macroH2A1.2; core histone macro-H2A.1
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Images |
Western blot analysis of extracts of various cell lines, using H2AFY antibody.
Immunohistochemistry of paraffin-embedded human kidney using mH2A1 antibody.
Immunohistochemistry of paraffin-embedded human kidney cancer using mH2A1 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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