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mH2A1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27054N-1 50ul / $395
APR27054N-2 100ul / $495
APR27054N-3 200ul / $595

mH2A1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27054N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality mH2A1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa Observed MW: 40kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human H2AFY (NP_613258.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

H2AFY; H2A.y; H2A/y; H2AF12M; MACROH2A1.1; mH2A1; macroH2A1.2; core histone macro-H2A.1

Images

Western blot analysis of extracts of various cell lines, using H2AFY antibody.

Immunohistochemistry of paraffin-embedded human kidney using mH2A1 antibody.

Immunohistochemistry of paraffin-embedded human kidney cancer using mH2A1 antibody.

Specification

Quantity

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