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CD68 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26631N-1 50ul / $395
APR26631N-2 100ul / $495
APR26631N-3 200ul / $595

CD68 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26631N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD68 Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/34kDa/37kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CD68 (NP_001242.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000IHC 1:50 - 1:200

Product Description

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Synonyms

CD68; GP110; LAMP4; SCARD1; macrosialin

Images

Immunohistochemistry of paraffin-embedded human tonsil using CD68 antibody.

Immunohistochemistry of paraffin-embedded human lung using CD68 antibody.

Immunohistochemistry of paraffin-embedded human appendix using CD68 antibody.

Specification

Quantity

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