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CD207 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26630N-1 50ul / $395
APR26630N-2 100ul / $495
APR26630N-3 200ul / $595

CD207 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26630N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD207 Polyclonal Antibody.

Molecular Weight

Calculated MW: 36kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CD207 (NP_056532.4).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Synonyms

CD207; CLEC4K; CD207 molecule

Images

Western blot analysis of extracts of various cell lines, using CD207 antibody.

Specification

Quantity

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