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PEX19 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25863N-1 50ul / $395
APR25863N-2 100ul / $495
APR25863N-3 200ul / $595

PEX19 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25863N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PEX19 Polyclonal Antibody.

Molecular Weight

Calculated MW: 29kDa/32kDa Observed MW: 37kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PEX19 (NP_002848.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Synonyms

PEX19; D1S2223E; HK33; PBD12A; PMP1; PMPI; PXF; PXMP1; peroxisomal biogenesis factor 19

Images

Western blot analysis of extracts of various cell lines, using PEX19 antibody.

Immunofluorescence analysis of mouse liver using PEX19 antibody.

Specification

Quantity

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