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OTX2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR25862N-1 50ul / $395
APR25862N-2 100ul / $495
APR25862N-3 200ul / $595

OTX2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR25862N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OTX2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/32kDa Observed MW: 32kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human OTX2 (NP_068374.1).

Cross Reactivity

Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Synonyms

OTX2; CPHD6; MCOPS5; homeobox protein OTX2

Images

Western blot analysis of extracts of various cell lines, using OTX2 antibody.

Specification

Quantity

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